This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans . The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans . With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.
?This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in bio gerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans. Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of health span, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine. This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.
A short read with 21 of the most important lessons from the relationship of Ruth and Boaz. The book has valuable lessons for men and women. The values they operated with in their day are still very much needed in the relationships of today. This read will challenge you to evaluate the way you date and enter into relationships.
Who are the most innovative and creative business leaders of all time? Names such as Thomas Edison, Steve Jobs, Nikola Tesla and Bill Gates usually come to mind, but Kingpin proposes an alternative. What if the most innovative and creative entrepreneurs operate on the fringe of business culture, outside the generally accepted confines of corporate organisation and governance? Despite the immoral, destructive and violent culture of the illicit drug trade, drug Kingpins are - first and foremost - entrepreneurs and risk managers. As pioneers of the underworld, they face unique challenges arising from the illegal nature of their trade. Their unpredictable and inherently risky world provides a wealth of diverse business challenges rarely encountered by mainstream business leaders. Thus they provide us with lessons that we can learn from no one else. The most successful Kingpins are visionary leaders who survive by implementing effective business strategies and policies. By suspending our judgement of the drug dealer and focusing on the Kingpin, we open our minds to their pioneering spirit.
The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combat degenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine.
Lessons From The Journey: From The Valley To Mountaintop is a Christian inspirational book where the author shares personal situations to help readers cope and triumph over tough times. The author warmly relates her own struggles in a four phase journey metaphor: The Valley, The Wilderness, The Ascent and The Mountaintop. With titles like You Are Allowed One Meltdown and The Process Is The Profit, the reader is sure to walk away with the tools needed meet and conquer the challenge.
This book reconstructs how claims to know the lessons from past wrongdoings are made useful in the present. These claims are powerful tools in contemporary debates over who we are, who we want to be and what we should do. Drawing on a wide range of spoken and written texts from Austria, Denmark, Germany and the United States, this book proposes an abstract framework through which such claims can be understood. It does so by conceptualising four rhetorics of learning and how each of them links memories of past wrongdoings to opposition to present and future wrongdoings. Drawing extensively on narrative theory, Lessons from the Past? reconstructs how links between past, present and future can be narrativised, thus helping to understand the subjectivities and feelings that these stories facilitate. The book closes by considering if and how such rhetorics might live up to their promise to know the lessons and to enable learning, offering a revised theory of collective learning processes. Bernhard Forchtner is Lecturer at the School of Media, Communication and Sociology, University of Leicester, UK. He has published in the field of memory studies, environmental communication, the far right in Europe and at the interface of sociological theory and critical discourse studies.
Great leaders have always understood the power of stories. Through the stories they tell, the most successful leaders educate, persuade and bring about change. In this hugely insightful guide to getting to the top, leading journalist Gavin Esler presents first-hand knowledge of the secrets of those who achieve power, based on over 30 years´ experience interviewing world famous figures, from Bill Clinton to Angelina Jolie.Esler explains how creating a leadership story can promote success at all levels, whether running for the United States presidency, or applying for a place at university. Spanning fields from business and culture to the military and even taking in lessons from terrorism, Lessons from the Top offers a fascinating portrait of leadership in the modern world - and shows how the methods of the most powerful leaders could work for you. 1. Language: English. Narrator: Gavin Esler. Audio sample: http://samples.audible.de/bk/bbcw/006206de/bk_rhde_002536_sample.mp3. Digital audiobook in aax.
Agrarian Development in Peasant Economies: Some Lessons from Kenya examines agrarian development in peasant, agricultural economies by focusing on Kenya and the lessons that can be learned from its experience. Topics covered include the beginnings of rural progress in Kenya; post-war agricultural policies and developments; the agrarian revolution; and the economics of peasant agriculture. Problems associated with agrarian reform are also discussed. This volume is comprised of seven chapters and begins with a historical background on Kenyas peasant agriculture, paying particular attention to the governments initiatives aimed at increasing agricultural production and controlling soil erosion. The next chapter deals with the countrys agricultural policies after World War II, including the implementation of a ten-year development plan and introduction of incentives to improve farming. Subsequent chapters look at the agrarian revolution in Kenya; certain features of peasant agriculture, including indigenous farming systems; the economics of the farm and the agricultural sector; and the policies pursued by the government to achieve agrarian development. The final chapter considers some of the issues affecting agrarian reform, including smallholding and rights of ownership and financing of rural development, in part by taxation. This monograph will be of interest to farmers and agriculturists as well as agricultural and economic policymakers.